Title: Isoniazid Toxicity in Dogs: Mechanism, Biochemistry, Clinical Manifestations, Treatment, and Antidote 1 – Mechanism of Isoniazid’s Antimicrobial Action and its Relation to Toxicity in

1 – Explain the mechanism of isoniazid’s antimicrobial action and how it relates to toxicity in dogs. 
2 – Discuss the unique dog biochemistry that promotes isoniazid toxicity in dogs. 
3 – Identify the organ system affected by isoniazid toxicity in dogs and describe clinical signs associated with the effects on these organs
4 – Describe the primary treatment approach to isoniazid toxicity and the antidote for isoniazid toxicosis. 
5 – Explain the mechanism of action of the antidote used when treating isoniazid toxicity. 
Must include the 5 components listed above. 
Must be 3-6 pages in length, Times New Roman size 12 font, double spaced, 1″ margins. 
Must include a minimum of 4 references. 

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